Acute respiratory tract infections

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Scope

What is the incidence of acute respiratory tract infections in the general population?

Definition

Rate (age, sex ratio) Context (population size studied, location, date data taken, end-point measured) Definition of end-point Reference
Incidence rates of first episodes of GP-diagnosed respiratory tract infections per 1000 person-years
All M F 0–4 years 5–14 yrs 15–49 yrs 50–64 yrs 65–74 years >74 years
Upper respiratory tract infections
Acute otitis media 15.6 16.3 15.0 135.9 33.5 5.4 3.2 2.7 1.6
Rhinitis 51.0 45.1 57.5 211.5 47.6 40.3 39.3 41.7 41.9
Acute sinusitis 22.7 15.7 29.9 2.9 7.4 29.7 25.8 17.2 9.6
Acute tonsillitis 10.2 8.7 11.7 25.8 13.6 12.0 3.2 2.3 0.8
Acute laryngitis 4.5 4.0 5.1 16.2 2.6 3.5 5.2 4.5 3.7
Lower respiratory tract infections
Acute bronchitis 19.9 18.6 21.5 55.4 14.0 12.8 21.8 31.8 42.0
Influenza 2.2 2.2 2.2 1.8 1.9 2.4 2.3 1.6 2.4
Pneumonia 6.4 6.7 6.2 16.6 4.8 3.2 6.1 12.5 21.6
Asthma /COPD exacerb. 1.4 1.4 1.5 3.7 1.0 0.7 1.5 3.5 3.7
Netherlands, 90 computerized general practices with 358 008 patients recorded consecutive patient contacts in a 12-month period between May 2000 and April 2002, doctor diagnosed ARIs Defined URTI GP-diagnoses as occurrence of acute otitis media (ICPC code H71), acute rhinitis (R74), acute sinusitis (R75), acute tonsillitis (R76) and acute laryngitis (R77). LRTI GP diagnoses defined as acute bronchitis (R78), influenza (R80), pneumonia (R81) or exacerbations of asthma or COPD (R78) [1]
Variables Number
Total ARI 984 (100)*
Fever 238 (24.2)
Runny/blocked nose 945 (96.0)
Cough 756 (76.8)
Rattly or wheezy chest 329 (33.4)
Wheeze present 95 (9.7)
Upper respiratory infections† 655 (66.6)
Lower respiratory infections 329 (33.4)
Nonwheezy LRI† 234 (23.8)
Wheezy LRI† 95 (9.7)
Physician visit 478 (48.6)
Hospitalization 17 (1.7)
RSV 5 (29.4)‡
Rhinoviruses 3 (17.6)‡
Parainfluenza 3 1 (5.9)‡
Influenza 1 (5.9)‡
Parainfluenza and RSV 1 (5.9)‡
Adenovirus 1 (5.9)‡
No virus detected 5 (29.4)‡
*Numbers in parentheses, percent.
†Mutually exclusive.
‡As % of hospitalized.
The majority reported 2–5 episodes of ARI in the first year (range = 0–11 episodes; mean = 4.1).
Study conducted btw July 1996 and July 1999, 263 infants at high risk of atopy (i.e. at least 1 parent with a doctor-diagnosed history of asthma, hay fever or eczema) followed until they reached 1yo. Australia, all ARIs. Parent diagnosed [2]

Result

See also

Wheeze studies
Prevalence of respiratory syncytial virus infection in italian infants hospitalized for acute lower respiratory tract infections
Chlamydia pneumoniae Infection Among Healthy Children and Children Hospitalised with Pneumonia in Greece
Prevalence of respiratory pathogens in children hospitalised with lower respiratory tract infection in Greece
Understanding the socioeconomic burden of human metapneumovirus in childhood
Nosocomial lower respiratory tract infections: prevalence and risk factors in 14 Greek hospitals
Human Metapneumovirus Associated with Respiratory Tract Infections in a 3-Year Study of Nasal Swabs from Infants in Italy

Related files

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References

  1. E Hak, MM Rovers, MM Kuyvenhoven, FG Schellevis and TJM Verheij. Incidence of GP-diagnosed respiratory tract infections according to age, gender and high-risk co-morbidity: the Second Dutch National Survey of General Practice. Family Practice Advance Access published on 7 February 2006.
  2. Merci M. H. Kusel, Nicholas H. de Klerk, Patrick G. Holt, Tatiana Kebadze, Sebastian L. Johnston, and Peter D. Sly. Role of Respiratory Viruses in Acute Upper and Lower Respiratory Tract Illness in the First Year of Life: A Birth Cohort Study. Pediatr Infect Dis J 2006;25: 680–686