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<accesscontrol>Members of projects,,Workshop2008,,beneris,,Erac,,Heimtsa,,Hiwate,,Intarese</accesscontrol>
[[Category:Intarese Guidance System]]
 
[[Category:Guidebook]]
{|
{{guidebook}}
|-
{| {{prettytable}}
| Parts of the Guidance system  
|Parts of the Guidance system
* '''Guidebook''' &#124; Categories: [[:Category:Guidebook|Guidebook]]
: [[Guidebook]] | Categories: [[:Category:Guidebook|Guidebook]]
* [[Glossary]] &#124; Categories: [[:Category:Glossary|Glossary]]
: [[Glossary]] | Categories: [[:Category:Glossary term|Glossary term]]
* [[Warehouse]] &#124; Categories: [[:Category:Assessments|Assessments]] &#124; [[:Category:Risk assessments|Risk assessments]] &#124; [[:Category:Variables|Variables]] &#124; [[:Category:Classes|Classes]]
: [[Warehouse]] | Categories: [[:Category:Assessments|Assessments]] | [[:Category:Risk assessments|Risk assessments]] | [[:Category:Variables|Variables]] | [[:Category:Classes|Classes]]
* [[Resource centre]] &#124; Categories: [[:Category:Resource centre|Resource centre]]
: [[Resource centre]] | Categories: [[:Category:Resource centre|Resource centre]]
 
|}
|}


== Table of Contents for the Guidebook ==
= Table of Contents for the Guidebook=
 
=== Guidebook main page ===


* short description of what the Guidebook (and Resource Centre) is
{{comment|#(number): |Due to a decision in the PSG in Intarese, the TOC of the Intarese Guidebook will partly heavily be changed. Therefore, I will start a new page for the "official system TOC" [http://pyrkilo.fi/intarese/index.php/Guidebook_TOC here] (Intarese wiki). It will be the basis for further discussions of WP 4.2 with SP 1. The [http://pyrkilo.fi/intarese/index.php/Resource_Centre_TOC Resource Centre Web page] will be the basis for communication with SP 2. |--[[User:Alexandra Kuhn|Alexandra Kuhn]] 15:47, 20 May 2008 (EEST)}}
* link to special pages ("menue" pages / interactive guidance) for the different user groups, e.g. policy makers, assessors, public
* link to the help
* link to the glossary
* ...


=== General assessment framework ===
==Guidebook main page==
: short description of what the [http://pyrkilo.fi/intarese/index.php/Guidebook_TOC Guidebook] [[:Intarese:Help:Guidebook on risk assessment| (old)]] (and Resource Centre) is
: link to [[Special:Specialpages|special pages]] ("menue" pages / interactive guidance) for the different user groups, e.g. policy makers, assessors, public
: link to the [[Help:Contents|help]]
: link to the [[Glossary|glossary]]
: ...


# Introduction  
==General assessment framework==
## Aim of the Guidebook WP 4.2
:Introduction
## Scope of the Guidebook WP 4.2
::Aim of the Guidebook WP 4.2
# [[General assessment framework]] | Categories: [[:Category:Assessment frameworks|Assessment frameworks]]  
::[[:Intarese:WP4.2_Guidance_system_Functionality|Scope of the Guidebook as stated in WP 4.2]]
## [[Purpose and properties of good assessments]] WP 1.1
:[[General assessment framework]] | Categories: [[:Category:Assessment frameworks|Assessment frameworks]]
## [[Societal context of assessments]]
::[[Purpose and properties of good assessments]] WP 1.1
## [[Evaluating assessment performance]]
::[[Societal context of assessments]] WP 1.1
## [[General assessment processes]] WP 1.1  
::[[Evaluating assessment performance]] WP 1.4
### Information processing {{reslink|Information processing methods by sub-processes}}  
::[[General assessment processes]] WP 1.1
#### Observing (actually belongs to basic science but is described here for completeness)
:::Information processing {{reslink|Information processing methods by sub-processes}}
#### Information collection
::::[[:en:Observation|Observing]] (actually belongs to basic science but is described here for completeness)
#### Information synthesis  
::::Information collection
##### Budding new objects
::::Information synthesis
##### Forming new classes
:::::[[Object design tool|Budding new objects]]
### Assessment process management  
:::::Forming new [[Class|classes]]
#### Assessment process phases
:::Assessment process management  
#### Process development
::::Assessment [[Process|process]] phases
## [[Universal products]] | Categories: [[:Category:Universal object|Universal object]] | [[:Category:Assessment objects|Assessment objects]]  
::::Process development
### [[Assessment]] | Categories: [[:Category:Assessments|Assessments]] | [[:Category:Risk assessments|Risk assessments]]
::[[Universal products]] | Categories: [[:Category:Universal object|Universal object]] | [[:Category:Assessment objects|Assessment objects]]
### [[Variable]] | Categories: [[:Category:Variables|Variables]]
:::[[Assessment]] | Categories: [[:Category:Assessments|Assessments]] | [[:Category:Risk assessments|Risk assessments]]
### [[Class]] | Categories: [[:Category:Classes|Classes]]
:::[[Variable]] | Categories: [[:Category:Variables|Variables]]
### Causal network
:::[[Class]] | Categories: [[:Category:Classes|Classes]]
:::[[Drawing a causal diagram|Causal network]]


=== Intarese framework ===
==Intarese framework==


# Intarese framework | Categories: [[:Category:Assessment methods|Assessment methods]] | [[:Category:Method|Method]] | [[:Category:Risk assessment methods|Risk assessment methods]] | [[:Category:Assessment tools|Assessment tools]] WP 1.1  
:[[Intarese framework]] | Categories: [[:Category:Assessment methods|Assessment methods]] | [[:Category:Method|Method]] | [[:Category:Risk assessment methods|Risk assessment methods]] |  
## Scientific context  
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=21 Assessment tools] WP 1.1
### Domain description  
::Scientific context
#### Full chain  
:::[[:Intarese:WP4.2 Technical Meeting|Domain description]]
##### Emissions
::::[[Template:Full chain approach|Full chain approach]]
##### Exposures
:::::[[:Intarese:Emission data|Emissions]]
##### Exposure-response function
:::::[[:Intarese:Exposure modelling|Exposure]] {{highlight|suggested to be released in Intarese-wiki}}
##### Health impacts and valuation
:::::[[Exposure-response relationship|Exposure-response function]]
## Policy context
:::::[[Health impact assessment|Health impacts]] and valuation
## Societal context
::[[:Intarese:Policy assessment protocols (Intarese method)|Policy context]]
## Technical context
::[[Societal context of assessments|Societal context]]
# [[Performing an assessment]] WP 1.1  
::[[:Intarese:Help:Technical specifications of Intarese toolbox|Technical context]]
## [[Issue framing]] | Tools: [[Issue framing tool]] WP 1.1  
:[[Performing an assessment]] WP 1.1
### [[Scoping an assessment]] WP 1.1  
::[[Issue framing]] | Tools: [[Issue framing tool]] WP 1.1
#### [[Defining the purpose of an assessment]]
:::[[Scoping an assessment]] WP 1.1
#### [[Defining the users of an assessment]]
::::[[Defining the purpose of an assessment]]
### [[Applying general information]] | Tools: [[Result database]]
::::[[Defining the users of an assessment]]
### [[Drawing a causal diagram]] WP 1.1 and 1.4
:::[[Applying general information]] | Tools: [[Result database]]
## [[Designing variables]] | Tools: [[Object design tool]] WP 1.4
:::[[Drawing a causal diagram]] WP 1.1 and 1.4
## [[Executing variables]] and [[Executing analyses|analyses]] | Tools: [[Analysis tool]] | [[External model tool]] | [[Extracted model tool]] | Uncertainty tool  
::[[Designing variables]] | Tools: [[Object design tool]] | [[Value judgement tool]] WP 1.4
### [[Variable transfer protocol]]
::[[Executing variables]] and [[Executing analyses|analyses]] | Tools: [[Analysis tool]] | [[External model tool]] | [[Extracted model tool]] | Uncertainty tool WP 1.1. and WP 1.4
## [[Reporting an assessment]] | Tools: [[Reporting tool]] WP 1.1 and WP 4.2
:::[[Variable transfer protocol]]
::[[Reporting an assessment]] | Tools: [[Reporting tool]] WP 1.1 and WP 4.2


=== General methods ===
==General methods==


# Processes that cover or relate to several phases or steps {{disclink|Methods by sub-processes}}  
:Processes that cover or relate to several phases or steps {{reslink|Information processing methods by sub-processes}}
## [[Participating in assessments]] WP 1.1 and 1.4  
::;[[Participating in assessments]] WP 1.1 and 1.4: The purpose is to allow participation in assessments in a way that ensures an effective distribution of tasks, successful aggregation of task outputs, and scientifically valid outcome.
### [[Mass collaboration]] | Tools: [[Collaborative workspace]] WP 1.4
:::;[[Mass collaboration]]: The purpose is the same as for participation in general, but allowing for '''open participation''' (see also [[Open Assessors' Network]]). | Tools: [[Collaborative workspace]] WP 1.4
### [[Organizing stakeholder involvement]] WP 1.1 and 1.4
:::;[[Organizing stakeholder involvement]] WP 1.1 and 1.4: The purpose is to collect information and value judgements about issues relevant for the assessment from stakeholders.
### Organizing assessment-policy collaboration
:::;Organizing assessment-policy collaboration: The purpose is the same as for [[organizing stakeholder involvement]] but limited to policy-makers. Does this include reporting to policy-makers?
### [[Dealing with disputes]] | Categories: [[:Category:Open discussions|Open discussions]] WP 1.1 and 1.4
:::;[[Dealing with disputes]]: The purpose is to deal with or resolve disputes about scientific or value-based issues that are relevant for the assessment.| Categories: [[:Category:Open discussions|Open discussions]] WP 1.1 and 1.4
## Expert panel/elicitation
::;[[:Intarese:Review of expert elicitation|Expert panel/elicitation]]: The purpose is to obtain quantitative data about an important variable in a situation where there are no measurements available. Experts of the area are interviewed and quantitative estimates are obtained from them. This also includes methods to evaluate the goodness of these elicited estimates.
## Multiple-bias modelling
::;[[:Intarese:Review of multiple-bias modelling|Multiple-bias modelling]]: The purpose is to correct the estimates based on general knowledge about biases that may or are likely to occur in the particular situation.
## GIS and spatial issues
::;[[:Intarese:Help:GIS tool|GIS]] {{highlight|(suggested to be released in Intarese)}} and spatial issues (WP 4.2): The purpose is...?
## [[Assessing uncertainty]] | Tools: Uncertainty tools (Aguila, MNP) {{disclink|Assessing uncertainty}}  
::;[[Assessing uncertainty]]: The purpose is to quantitatively assess the uncertainties related to the variables of interest. | Tools: Uncertainty tools (Aguila, [http://www.intarese.org/kt/view.php?fDocumentId=92| MNP], [[:Intarese:Help:Sensitivity analysis|Sensitivity analysis]], [[:Intarese:Monte Carlo simulation|Monte Carlo simulation]], [[:Intarese:Bayesian analysis|Bayesian analysis]], [[:Intarese:Bayesian belief networks|Bayesian belief networks]] and [[:Intarese:Bayesian hierarchical modelling|Bayesian hierarchical modelling]]) {{disclink|Assessing uncertainty}} What about the uncertainties of an assessment and error propagation?
### Estimating uncertainties WP 1.5
:::;Estimating uncertainties WP 1.5: The purpose is to... what is the difference to assessing uncertainty? Maybe, assessing uncertainties is more like an introductory article and also includes qualitative analyses while estimating uncertainties will include only quantitative analyses?
### Propagating uncertainties WP 1.5 (but will WP 1.5 cover this at all?)
:::;[[Uncertainty modeling in dose response|Propagating uncertainties]] WP 1.5 (but will WP 1.5 cover this at all?): The purpose is to quantitatively propagate the uncertainties (described as probability distributions) through the model in a way that the uncertainties of all parts of the model are coherently described.
### Value of information analysis WP 1.4
:::;Reporting uncertainties WP 1.5
## [[Collective structured learning]] | Tools: [[Result database]] {{disclink|Tools in guidebook}}
:::;[[:Intarese:Value of information|Value of information]] analysis WP 1.4: The purpose is to quantitatively estimate the value of further information (VOI) for decision-making. The VOI is always estimated for a particular set of decision options, using a defined outcome. It may be calculated for the whole decision situation (value of information) or a particular variable (value of partial information).
## [[Quality assurance and quality control]] | Categories: [[:Category:Pages of assessed quality|Pages of assessed quality]]
::;[[Collective structured learning]]: The purpose is to utilise existing information from previous assessments directly in new assessments and thus reduce costs of making assessments. This is done using two principles: the information is given freely available, and the information is structured in a uniform way. | Tools: [[Result database]] {{disclink|Tools in guidebook}} WP 1.4
::;[[Quality assurance and quality control]]: The purpose is to evaluate and ensure that the assessment fulfils the scientific criteria. An assessment is considered quality-controlled if all its parts are acceptably peer-reviewed and found out to fulfil the state-of-the art, or alternatively if a part does not fulfil the state-of-the-art, it is shown that the quality defect does not influence the conclusions.  | Categories: [[:Category:Pages of assessed quality|Pages of assessed quality]] WP 1.4


=== Methods related to a particular step in the full chain ===
==Methods related to a particular step in the full chain==


# Methods related to a particular step in the full chain | Categories: [[:Category:First level scoping objects|First level scoping objects]] {{disclink|Processes and products in guidebook}} {{reslink|Step-specific methods}} {{disclink|Methods by sub-processes}}  
:Methods related to a particular step in the full chain | Categories: [[:Category:First level scoping objects|First level scoping objects]] {{disclink|Processes and products in guidebook}} {{reslink|Step-specific methods}} {{reslink|Information processing methods by sub-processes}}
## Activity modelling | Categories: [[:Category:Policy options|Policy options]] | [[:Category:Activities|Activities]]
## Emission modelling | Categories: [[:Category:Pollutants|Pollutants]] | [[:Category:Emission releases|Emission releases]] | [[:Category:Emission sources|Emission sources]] | [[:Category:Emission factors and activities|Emission factors and activities]] WP 4.2 and 2.x (<span style="color: rgb(255, 170, 187);">estimation of emissions into different media due to activities / driving forces</span>)
### including emission scenario building???
## Source-to-exposure modelling / environmental fate modelling | Categories: [[:Category:Fate and transport|Fate and transport]] | [[:Category:Pathway media|Pathway media]] | [[:Category:Concentrations in the environment|Concentrations in the environment]] WP 1.2
### Atmospheric environmental fate models /dispersion models (<span style="color: rgb(255, 170, 187);">estimation of concentration in air due to releases into air</span>)
### Multimedia environmental fate models (<span style="color: rgb(255, 170, 187);">estimation of concentration in env. media due to releases into the media</span>)
### Intake fraction (<span style="color: rgb(255, 170, 187);">relating intake to emissions</span>)
### Source apportionment (<span style="color: rgb(255, 170, 187);">for a given concentration find the related pollutant sources</span>)
## Exposure modelling | Categories: | [[:Category:Exposures|Exposures]] | [[:Category:Population behaviour|Population behaviour]] WP 1.2 (<span style="color: rgb(255, 170, 187);">estimation of the exposure of the population, disaggreated by pollutants/stressors, micorenvironments, times, ...</span>)
### including exposure scenarios
## Internal dose modelling | Categories: [[:Category:Doses|Doses]] WP 1.3 and WP 2.2
### Pharmacokinetic modelling
### Biomonitoring
## Exposure-response function modelling | Categories: [[:Category:Health effects|Health effects]] | [[:Category:Exposure-response functions|Exposure-response functions]] WP 1.3 and 2.2 and 2.3
### Performing meta-analysis (<span style="color: rgb(255, 170, 187);">deriving ERFs from several studies</span>)
### Combining toxicological and epidemiological information (<span style="color: rgb(255, 170, 187);">deriving better ERFs/DRFs</span>)
## Background incidence estimation
## Health impact valuation | Categories: [[:Category:Costs and valuations|Costs and valuations]] WP 1.4
### Risk appraisal framework | Categories: [[:Category:Appraisal|Appraisal]]
#### Distance to (regulatory) target (<span style="color: rgb(255, 170, 187);">define, if a policy/measures are suitable to fulfill a given target and/or how far the actual/modelled situation is from the target situation</span>)
#### Impact estimation | Categories: [[:Category:Non-health impacts|Non-health impacts]] {{comment|#(number): |???|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 17:11, 7 March 2008 (EET)}}
#### Monetary estimation {{comment|#(number): |???|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 17:11, 7 March 2008 (EET)}}
#### Risk perception and acceptability {{comment|#(number): |below is also perception|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 17:11, 7 March 2008 (EET)}}
#### Equity estimation {{comment|#(number): |below is also equitiy issues|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 17:11, 7 March 2008 (EET)}}
### Burden of disease measures {{comment|#(number): |Could we accumulate it like this?|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 17:11, 7 March 2008 (EET)}}
#### Disability-adjusted life years (<span style="color: rgb(255, 170, 187);">summarized burden of disease adding up increased mortality (years of life lost) and years lived with disability: DALY translates the impacts of diseases into life years based on their severity and duration, so that different diseases can be measured using a single currency, the life year.</span>)
#### Quality-adjusted life years (<span style="color: rgb(255, 170, 187);">QALYs evaluate the quality of life in a certain health state, not disease</span>)
### Monetary valuation (<span style="color: rgb(255, 170, 187);">Possibility to compare and/or aggregate different impacts (e.g. health endpoints, cancer case, cough day, biodiversity loss</span>). Weighing of impacts; convert everything to one unit (to make it comparable))
#### Discounting
#### Transferability of monetary values (<span style="color: rgb(255, 170, 187);">making monetary values usable in another context (e.g. country)</span>)
#### Contingent valuation studies (CVS) (<span style="color: rgb(255, 170, 187);">Determining the willingness to pay (monet. values) for goods/utility changes that are not traded on the market, e.g. health effects. In principle this is not contrained to ask for WTP, is it???</span>)
##### WTP (<span style="color: rgb(255, 170, 187);">Preference of the population to avoid utility change; weighing, e.g. health effects</span>)
### Including value judgements (<span style="color: rgb(255, 170, 187);">being able to compare s.th. in including judgements about values; preferences</span>)
#### Risk perception (<span style="color: rgb(255, 170, 187);">is this a process or product?;&nbsp;???</span>)
#### Equity issues


=== Related frameworks and issues ===
===Environment / Pressures===


# Related assessment frameworks
:Activity modelling | Categories: [[:Category:Policy options|Policy options]] | [[:Category:Activities|Activities]]
## Impact assessment
:Emission modelling | Categories: [[:Category:Pollutants|Pollutants]] | [[:Category:Emission releases|Emission releases]] | [[:Category:Emission sources|Emission sources]] | [[:Category:Emission factors and activities|Emission factors and activities]] WP 4.2 and 2.x {{highlight|(estimation of emissions into different media due to activities / driving forces)}}
## Chemical risk assessment
::including emission scenario building???
## Cumulative risk assessment (U.S.EPA)
:[[:Intarese:Exposure modelling|Source-to-exposure modelling]] / environmental fate modelling | Categories: [[:Category:Fate and transport|Fate and transport]] | [[:Category:Pathway media|Pathway media]] | [[:Category:Concentrations in the environment|Concentrations in the environment]] WP 1.2
## Cost-benefit or benefit-cost analysis {{reslink|Frameworks in guidebook}} (<span style="color: rgb(255, 170, 187);">to overall compare different options, taking into account costs and benefits</span>)
::Atmospheric environmental fate models /dispersion models {{highlight|(estimation of concentration in air due to releases into air)}}
## Cost-effectiveness analysis (<span style="color: rgb(255, 170, 187);">to compare different options that have the same aim; the effects are not compared in monetary values</span>)
::Multimedia environmental fate models {{highlight|(estimation of concentration in env. media due to releases into the media)}}
## Multi-attribute utility analysis
::[[:Intarese:Intake fraction method review|Intake fraction]] {{highlight|(relating intake to emissions)}}
# Other important issues that are outside Intarese framework
::[[:Intarese:Source-apportionment method review|Source attribution]] {{highlight|(for a given concentration find the related pollutant sources)}}
## Global warming
:::[[:Intarese:D-37 Database of source apportionment and iF-modeling studies|Database of source attribution]] {{highlight|suggested to be released from Intarese-wiki}}
## Accidents
## Ecosystems and biodiversity


== Pages available for release in Intarese ==
===Human / Exposure-Response modelling===


* See [http://www.pyrkilo.fi/intarese/index.php/Category:To_be_released Intarese:Category:To be released] for pages that should be moved to Heande and taken as part of the Guidance system.
:[[:Intarese:Exposure modelling|Exposure modelling]] {{highlight| (a page suggested to be released in Intarese)}} | Categories:  | [[:Category:Exposures|Exposures]] | [[:Category:Population behaviour|Population behaviour]] WP 1.2 {{highlight|(estimation of the exposure of the population, disaggregated by pollutants/stressors, microenvironments, times, ...)}}
* See [http://www.pyrkilo.fi/intarese/index.php/Category:Release_suggested Intarese:Category:Release suggested] for pages that should be moved to Heande but the content owner has not yet given the permission.
::including exposure scenarios:
:::[http://www.intarese.org/kt/view.php?fDocumentId=137 Exposure Evaluation Report]<br>
:::[http://www.intarese.org/kt/view.php?fDocumentId=136 Source-to-exposure and Source Attribution Modelling Methodologies (D13 & D14)]
:::[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=32 Exposure-source Apportionment and iF-Database (D37 Final, July 2007)]
:Internal dose modelling | Categories: [[:Category:Doses|Doses]] WP 1.3 and WP 2.2
::Pharmacokinetic modelling
::Biomonitoring
:[[Multistage model|Exposure-response function modelling]] | Categories: [[:Category:Health effects|Health effects]] | [[:Category:Exposure-response functions|Exposure-response functions]] WP 1.3 and 2.2 and 2.3
::Performing [[:Intarese:Review of meta-analysis|meta-analysis]] {{highlight|(deriving ERFs from several studies)}}
::[[:Intarese:Intarese:R86 Combining epidemiology and toxicology|Combining toxicological and epidemiological information]] {{highlight|(deriving better ERFs/DRFs)}}


=== The pages of the Pyrkilo guide 2 ===
===Valuation / Aggregation===


The table contains all pages that are attached to the [http://www.pyrkilo.fi/intarese/index.php/Help:Pyrkilo_guide_2 Intarese:Help:Pyrkilo guide 2] page. The second column (where it should go) talks about where the current content of the page should go. It does not imply that the scopes of the old and the new page should be the same.
:Non-health impact estimation  | Categories: [[:Category:Non-health impacts|Non-health impacts]]  {{highlight|This is outside Intarese framework but should be mentioned}}
:Health impact valuation | Categories: [[:Category:Costs and valuations|Costs and valuations]] WP 1.4
::[[:Intarese:Appraisal Framework for Environment and Health|Risk appraisal framework]] {{highlight|consists of five panels that are briefly listed here but described in more detail elsewhere}} | Categories: [[:Category:Appraisal|Appraisal]] {{attack|#(number): |I think this belongs more to the Intarese framework than here as it encompasses much more than the step of aggregation and valuation|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 18:43, 21 May 2008 (EEST)}}
::: Policy impact valuation, e.g. Distance to (regulatory) target {{highlight|(define, if a policy/measures are suitable to fulfill a given target and/or how far the actual/modelled situation is from the target situation)}}
:::Health impact estimation
:::[[:Intarese:Monetary values for impacts to human health|Monetary impact estimation]]
:::Perception and acceptability impact estimation
:::Equity estimation
::Burden of disease measures  {{comment|#1: |Could we accumulate it like this?|--[[User:Alexandra Kuhn|Alexandra Kuhn]] 17:11, 7 March 2008 (EET)}}
:::[[:Intarese:Disability-adjusted life years|Disability-adjusted life years]] {{highlight|(summarized burden of disease adding up increased mortality (years of life lost) and years lived with disability: DALY translates the impacts of diseases into life years based on their severity and duration, so that different diseases can be measured using a single currency, the life year.)}}
:::[[:en:Quality-adjusted life years|Quality-adjusted life years]] {{highlight|(QALYs evaluate the quality of life in a certain health state, not disease)}}
::[[:Intarese:Monetization of impacts|Monetary valuation]] {{highlight|(Possibility to compare and/or aggregate different impacts (e.g. health endpoints, cancer case, cough day, biodiversity loss)}}. Weighing of impacts; convert everything to one unit (to make it comparable))
:::[[Discount|Discounting]]
:::Transferability of monetary values {{highlight|(making monetary values usable in another context (e.g. country))}}
:::Contingent valuation studies (CVS) {{highlight|(Determining the willingness to pay (monet. values) for goods/utility changes that are not traded on the market, e.g. health effects. In principle this is not contrained to ask for WTP, is it???)}}
::::WTP {{highlight|(Preference of the population to avoid utility change; weighing, e.g. health effects)}}
::[[Value judgement tool|Including value judgements]] {{highlight|(being able to compare s.th. in including judgements about values; preferences)}}
:::[[:Intarese:Risk perception|Risk perception]] {{highlight|(is this a process or product?; ???)}}
:::Equity issues


{|
==Related frameworks and issues==
|+ In the Guidebook
|-
| The location in Intarese (links redirect to the current page)
| Where it is now
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Analysis_tool Intarese:Help:Analysis tool]
| Tool:Analysis tool
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Applying_general_information Intarese:Help:Applying general information]
| Method:Applying general information
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Class Intarese:Help:Class]
| Universal products:Class
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Collaborative_workspace Intarese:Help:Collaborative workspace]
| Tool:Collaborative workspace
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Designing_variables Intarese:Help:Designing variables]
| Method:Designing variables
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Dispute Intarese:Help:Dispute]
| Method:Dealing with disputes
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Drawing_a_causal_diagram Intarese:Help:Drawing a causal diagram]
| Method:Drawing a causal diagram
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Executing_variables Intarese:Help:Executing variables]
| Method:Executing variables
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:External_model Intarese:Help:External model]
| Tool:External model
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Extracted_model Intarese:Help:Extracted model]
| Tool:Extracted model
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Issue_framing_tool Intarese:Help:Issue framing tool]
| Tool:Issue framing tool
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Mass_collaboration Intarese:Help:Mass collaboration]
| Method:Mass collaboration
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Model_extractor Intarese:Help:Model extractor]
| Tool:Extracted model tool
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Object_design_tool Intarese:Help:Object design tool]
| Tool:Object design tool
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Purpose_of_a_risk_assessment Intarese:Help:Purpose of a risk assessment]
| Method:Defining the purpose of an assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Reporting_a_risk_assessment Intarese:Help:Reporting a risk assessment]
| Method:Reporting an assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Reporting_tool Intarese:Help:Reporting tool]
| Tool:Reporting tool
|-
| [[Help:Result database]]
| Tool:Result database
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Risk_assessment_structure Intarese:Help:Risk assessment structure]
| Universal product:Assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Scoping_a_risk_assessment Intarese:Help:Scoping a risk assessment]
| Method:Scoping an assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:The_phases_of_a_risk_assessment Intarese:Help:The phases of a risk assessment]
| Method:Performing an assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Universal_information_structure_for_risk_assessment_products Intarese:Help:Universal information structure for risk assessment products]
| Theoretical foundation:Universal products
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Users_of_the_pyrkilo_method Intarese:Help:Users of the pyrkilo method]
| Method:Defining the users of an assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Variable Intarese:Help:Variable]
| Universal products:Variable
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Variable_transfer_protocol Intarese:Help:Variable transfer protocol]
| Method:Variable transfer protocol
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Managing_stakeholder_involvement Intarese:Help:Managing stakeholder involvement]
| Method:Organizing stakeholder information
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Variable_definition Intarese:Help:Variable definition]
| Universal products:Variable
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Plausibility_tests Intarese:Help:Plausibility tests]
| Universal products:Variable
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:General_properties_of_good_risk_assessments Intarese:Help:General properties of good risk assessments]
| General assessment framework:Purpose and properties of good assessments
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Performance Intarese:Help:Performance]
| General assessment framework:Evaluating assessment performance
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Societal_role_of_risk_assessment Intarese:Help:Societal role of risk assessment]
| General assessment framework:Societal context of assessments
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Open_participation_in_risk_assessment Intarese:Help:Open participation in risk assessment]
| Method:Participating in assessments
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Risk_assessment_process Intarese:Help:Risk assessment process]
| Theoretical foundation:General processes
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Uncertainty Intarese:Help:Uncertainty]
| Method:Assessing uncertainty
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Contributing_to_a_discussion Intarese:Help:Contributing to a discussion]
| Method:Dealing with disputes
|}


<br>
:Related assessment frameworks
::Impact assessment
::[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=33 Chemical risk assessment]
::[http://www.epa.gov/OSA/spc/2cumrisk.htm| Cumulative risk assessment (U.S.EPA CRA program)]
::[[:Intarese:CBA|Cost-benefit analysis]] {{reslink|Frameworks in guidebook}} {{highlight|(to overall compare different options, taking into account costs and benefits)}}
::[[:Intarese:CBA|Cost-effectiveness analysis]] {{highlight|(to compare different options that have the same aim; the effects are not compared in monetary values)}}
::Multi-attribute utility analysis
:Other important issues that are outside Intarese framework
::[[:Intarese:Climate change|Global warming]]
::Accidents
::Ecosystems and biodiversity


{|
==Other related documents==
|+ In other parts of the Guidance system
|-
| The location in Intarese (links redirect to the current page)
| Where it is now
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Causality Intarese:Help:Causality]
| Glossary:Causality
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Decision_variable Intarese:Help:Decision variable]
| Glossary:Decision variable
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Value_judgement Intarese:Help:Value judgement]
| Glossary:Value judgement
|}


<br>
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=135 Personal monitoring detailed review PM and NO<sub>2</sub>] (Detailed review of EXOPLIS and ULTRA for PM<sub>2.5</sub> and NO<sub>2</sub>)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=123 WP3.3 protocol] (Agricultural land use, policy assessment protocol) and related [http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=124 list of key data sets]
::[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=128 IC Pesticide Modelling Approach]
::[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=122 Pesticide evaluation report]
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=18 Risk Characterisation Protocol] (D16 Final, May 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=30 Risk Characterisation Methodology Report] (D17 Final, June 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=14  Environmental Monitoring Review] (D19 Final, Sept 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=28 Human Biomarker Review and Development Strategy] (D20 Final, June 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=22 Health Data Review and Surveillance Strategy] (D21 Final, Sept 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=15 Transport Assessment Protocol] (D22, September 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=23 D23 Housing Assessment Protocol] (D23 Final, May 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=25  Water Assessment Protocol] (D25 Final, Sept 07)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=27 Wastes Assessment Protocol] (D27 Final, May 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=16 Climate Assessment Protocol] (D28 Final, May 2007)
:[http://www.intarese.org/kt/action.php?kt_path_info=ktcore.actions.document.view&fDocumentId=19 User Analysis] for appropriate evaluation and sensible prioritisation of integrated assessment of health risks within the European public health approaches (D29, Sept 2007)
:[http://www.intarese.org/secure-area/key-readings.htm Key readings on integrated assessments]


{|
=Pages available for release in Intarese=
|+ The new location not yet clear
|-
| The current location in Intarese
| Where it should go
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Copyright_issues Intarese:Help:Copyright issues]
| Method:Dealing with copyright issues
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Data_gateway Intarese:Help:Data gateway]
| Tool:Data gateway
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Encyclopedia_on_environmental_health Intarese:Help:Encyclopedia on environmental health]
| Glossary:Encyclopedia on environmental health
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Guidebook_on_risk_assessment Intarese:Help:Guidebook on risk assessment]
| Glossary:Guidebook
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Integrated_resource_platform Intarese:Help:Integrated resource platform]
| Glossary:Resource platform
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Open_risk_assessment_%28toolbox%29 Intarese:Help:Open risk assessment (toolbox)]
| Glossary:Open assessment
|-
| [http://www.pyrkilo.fi/intarese/index.php/Help:Pyrkilo_method_%28summary%29 Intarese:Help:Pyrkilo method (summary)]
| Glossary:Pyrkilo method
|}


[[Category:Guidebook]]
:See [[:Intarese:Category:To be released]] for pages that should be moved to Opasnet and taken as part of the Guidance system.
:See [[:Intarese:Category:Release suggested]] for pages that should be moved to Opasnet but the content owner has not yet given the permission.

Latest revision as of 11:41, 24 October 2008

Parts of the Guidance system
Guidebook | Categories: Guidebook
Glossary | Categories: Glossary term
Warehouse | Categories: Assessments | Risk assessments | Variables | Classes
Resource centre | Categories: Resource centre

Table of Contents for the Guidebook

----#(number):: . Due to a decision in the PSG in Intarese, the TOC of the Intarese Guidebook will partly heavily be changed. Therefore, I will start a new page for the "official system TOC" here (Intarese wiki). It will be the basis for further discussions of WP 4.2 with SP 1. The Resource Centre Web page will be the basis for communication with SP 2. --Alexandra Kuhn 15:47, 20 May 2008 (EEST) (type: truth; paradigms: science: comment)

Guidebook main page

short description of what the Guidebook (old) (and Resource Centre) is
link to special pages ("menue" pages / interactive guidance) for the different user groups, e.g. policy makers, assessors, public
link to the help
link to the glossary
...

General assessment framework

Introduction
Aim of the Guidebook WP 4.2
Scope of the Guidebook as stated in WP 4.2
General assessment framework | Categories: Assessment frameworks
Purpose and properties of good assessments WP 1.1
Societal context of assessments WP 1.1
Evaluating assessment performance WP 1.4
General assessment processes WP 1.1
Information processing R↻
Observing (actually belongs to basic science but is described here for completeness)
Information collection
Information synthesis
Budding new objects
Forming new classes
Assessment process management
Assessment process phases
Process development
Universal products | Categories: Universal object | Assessment objects
Assessment | Categories: Assessments | Risk assessments
Variable | Categories: Variables
Class | Categories: Classes
Causal network

Intarese framework

Intarese framework | Categories: Assessment methods | Method | Risk assessment methods |
Assessment tools WP 1.1
Scientific context
Domain description
Full chain approach
Emissions
Exposure suggested to be released in Intarese-wiki
Exposure-response function
Health impacts and valuation
Policy context
Societal context
Technical context
Performing an assessment WP 1.1
Issue framing | Tools: Issue framing tool WP 1.1
Scoping an assessment WP 1.1
Defining the purpose of an assessment
Defining the users of an assessment
Applying general information | Tools: Result database
Drawing a causal diagram WP 1.1 and 1.4
Designing variables | Tools: Object design tool | Value judgement tool WP 1.4
Executing variables and analyses | Tools: Analysis tool | External model tool | Extracted model tool | Uncertainty tool WP 1.1. and WP 1.4
Variable transfer protocol
Reporting an assessment | Tools: Reporting tool WP 1.1 and WP 4.2

General methods

Processes that cover or relate to several phases or steps R↻
Participating in assessments WP 1.1 and 1.4
The purpose is to allow participation in assessments in a way that ensures an effective distribution of tasks, successful aggregation of task outputs, and scientifically valid outcome.
Mass collaboration
The purpose is the same as for participation in general, but allowing for open participation (see also Open Assessors' Network). | Tools: Collaborative workspace WP 1.4
Organizing stakeholder involvement WP 1.1 and 1.4
The purpose is to collect information and value judgements about issues relevant for the assessment from stakeholders.
Organizing assessment-policy collaboration
The purpose is the same as for organizing stakeholder involvement but limited to policy-makers. Does this include reporting to policy-makers?
Dealing with disputes
The purpose is to deal with or resolve disputes about scientific or value-based issues that are relevant for the assessment.| Categories: Open discussions WP 1.1 and 1.4
Expert panel/elicitation
The purpose is to obtain quantitative data about an important variable in a situation where there are no measurements available. Experts of the area are interviewed and quantitative estimates are obtained from them. This also includes methods to evaluate the goodness of these elicited estimates.
Multiple-bias modelling
The purpose is to correct the estimates based on general knowledge about biases that may or are likely to occur in the particular situation.
GIS (suggested to be released in Intarese) and spatial issues (WP 4.2)
The purpose is...?
Assessing uncertainty
The purpose is to quantitatively assess the uncertainties related to the variables of interest. | Tools: Uncertainty tools (Aguila, MNP, Sensitivity analysis, Monte Carlo simulation, Bayesian analysis, Bayesian belief networks and Bayesian hierarchical modelling) D↷ What about the uncertainties of an assessment and error propagation?
Estimating uncertainties WP 1.5
The purpose is to... what is the difference to assessing uncertainty? Maybe, assessing uncertainties is more like an introductory article and also includes qualitative analyses while estimating uncertainties will include only quantitative analyses?
Propagating uncertainties WP 1.5 (but will WP 1.5 cover this at all?)
The purpose is to quantitatively propagate the uncertainties (described as probability distributions) through the model in a way that the uncertainties of all parts of the model are coherently described.
Reporting uncertainties WP 1.5
Value of information analysis WP 1.4
The purpose is to quantitatively estimate the value of further information (VOI) for decision-making. The VOI is always estimated for a particular set of decision options, using a defined outcome. It may be calculated for the whole decision situation (value of information) or a particular variable (value of partial information).
Collective structured learning
The purpose is to utilise existing information from previous assessments directly in new assessments and thus reduce costs of making assessments. This is done using two principles: the information is given freely available, and the information is structured in a uniform way. | Tools: Result database D↷ WP 1.4
Quality assurance and quality control
The purpose is to evaluate and ensure that the assessment fulfils the scientific criteria. An assessment is considered quality-controlled if all its parts are acceptably peer-reviewed and found out to fulfil the state-of-the art, or alternatively if a part does not fulfil the state-of-the-art, it is shown that the quality defect does not influence the conclusions. | Categories: Pages of assessed quality WP 1.4

Methods related to a particular step in the full chain

Methods related to a particular step in the full chain | Categories: First level scoping objects D↷ R↻ R↻

Environment / Pressures

Activity modelling | Categories: Policy options | Activities
Emission modelling | Categories: Pollutants | Emission releases | Emission sources | Emission factors and activities WP 4.2 and 2.x (estimation of emissions into different media due to activities / driving forces)
including emission scenario building???
Source-to-exposure modelling / environmental fate modelling | Categories: Fate and transport | Pathway media | Concentrations in the environment WP 1.2
Atmospheric environmental fate models /dispersion models (estimation of concentration in air due to releases into air)
Multimedia environmental fate models (estimation of concentration in env. media due to releases into the media)
Intake fraction (relating intake to emissions)
Source attribution (for a given concentration find the related pollutant sources)
Database of source attribution suggested to be released from Intarese-wiki

Human / Exposure-Response modelling

Exposure modelling (a page suggested to be released in Intarese) | Categories: | Exposures | Population behaviour WP 1.2 (estimation of the exposure of the population, disaggregated by pollutants/stressors, microenvironments, times, ...)
including exposure scenarios:
Exposure Evaluation Report
Source-to-exposure and Source Attribution Modelling Methodologies (D13 & D14)
Exposure-source Apportionment and iF-Database (D37 Final, July 2007)
Internal dose modelling | Categories: Doses WP 1.3 and WP 2.2
Pharmacokinetic modelling
Biomonitoring
Exposure-response function modelling | Categories: Health effects | Exposure-response functions WP 1.3 and 2.2 and 2.3
Performing meta-analysis (deriving ERFs from several studies)
Combining toxicological and epidemiological information (deriving better ERFs/DRFs)

Valuation / Aggregation

Non-health impact estimation | Categories: Non-health impacts This is outside Intarese framework but should be mentioned
Health impact valuation | Categories: Costs and valuations WP 1.4
Risk appraisal framework consists of five panels that are briefly listed here but described in more detail elsewhere | Categories: Appraisal ⇤--#(number):: . I think this belongs more to the Intarese framework than here as it encompasses much more than the step of aggregation and valuation --Alexandra Kuhn 18:43, 21 May 2008 (EEST) (type: truth; paradigms: science: attack)
Policy impact valuation, e.g. Distance to (regulatory) target (define, if a policy/measures are suitable to fulfill a given target and/or how far the actual/modelled situation is from the target situation)
Health impact estimation
Monetary impact estimation
Perception and acceptability impact estimation
Equity estimation
Burden of disease measures ----#1:: . Could we accumulate it like this? --Alexandra Kuhn 17:11, 7 March 2008 (EET) (type: truth; paradigms: science: comment)
Disability-adjusted life years (summarized burden of disease adding up increased mortality (years of life lost) and years lived with disability: DALY translates the impacts of diseases into life years based on their severity and duration, so that different diseases can be measured using a single currency, the life year.)
Quality-adjusted life years (QALYs evaluate the quality of life in a certain health state, not disease)
Monetary valuation (Possibility to compare and/or aggregate different impacts (e.g. health endpoints, cancer case, cough day, biodiversity loss). Weighing of impacts; convert everything to one unit (to make it comparable))
Discounting
Transferability of monetary values (making monetary values usable in another context (e.g. country))
Contingent valuation studies (CVS) (Determining the willingness to pay (monet. values) for goods/utility changes that are not traded on the market, e.g. health effects. In principle this is not contrained to ask for WTP, is it???)
WTP (Preference of the population to avoid utility change; weighing, e.g. health effects)
Including value judgements (being able to compare s.th. in including judgements about values; preferences)
Risk perception (is this a process or product?; ???)
Equity issues

Related frameworks and issues

Related assessment frameworks
Impact assessment
Chemical risk assessment
Cumulative risk assessment (U.S.EPA CRA program)
Cost-benefit analysis R↻ (to overall compare different options, taking into account costs and benefits)
Cost-effectiveness analysis (to compare different options that have the same aim; the effects are not compared in monetary values)
Multi-attribute utility analysis
Other important issues that are outside Intarese framework
Global warming
Accidents
Ecosystems and biodiversity

Other related documents

Personal monitoring detailed review PM and NO2 (Detailed review of EXOPLIS and ULTRA for PM2.5 and NO2)
WP3.3 protocol (Agricultural land use, policy assessment protocol) and related list of key data sets
IC Pesticide Modelling Approach
Pesticide evaluation report
Risk Characterisation Protocol (D16 Final, May 2007)
Risk Characterisation Methodology Report (D17 Final, June 2007)
Environmental Monitoring Review (D19 Final, Sept 2007)
Human Biomarker Review and Development Strategy (D20 Final, June 2007)
Health Data Review and Surveillance Strategy (D21 Final, Sept 2007)
Transport Assessment Protocol (D22, September 2007)
D23 Housing Assessment Protocol (D23 Final, May 2007)
Water Assessment Protocol (D25 Final, Sept 07)
Wastes Assessment Protocol (D27 Final, May 2007)
Climate Assessment Protocol (D28 Final, May 2007)
User Analysis for appropriate evaluation and sensible prioritisation of integrated assessment of health risks within the European public health approaches (D29, Sept 2007)
Key readings on integrated assessments

Pages available for release in Intarese

See Intarese:Category:To be released for pages that should be moved to Opasnet and taken as part of the Guidance system.
See Intarese:Category:Release suggested for pages that should be moved to Opasnet but the content owner has not yet given the permission.