Lung cancer: Difference between revisions

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| Simonato L, Agudo A, Ahrens W, et al. Lung cancer and cigarette smoking in Europe: an update of risk estimates and an assessment of inter-country heterogeneity. Int J Cancer 2001; 91: 876–87.
| Simonato L, Agudo A, Ahrens W, et al. Lung cancer and cigarette smoking in Europe: an update of risk estimates and an assessment of inter-country heterogeneity. Int J Cancer 2001; 91: 876–87.
|----
|----
{| {{prettytable}}
|{| {{prettytable}}
| colspan="12"| Number of new cases and rates of lung cancer,                    UK, 2006
| colspan="12"| Number of new cases and rates of lung cancer,                    UK, 2006
|----
|----
|
|
| colspan="2"| England
| colspan="2" align="center"| England
| colspan="2"| Wales
| colspan="2" align="center"| Wales
| colspan="2"| Scotland
| colspan="2" align="center"| Scotland
| colspan="2"| N.Ireland
| colspan="2" align="center"| N.Ireland
| colspan="2"| UK
| colspan="2" align="center"| UK
|----
|----
| colspan="12"| Cases
| colspan="12"| Cases
|----
|----
| Males
| Males
| colspan="2"| 18,026
| colspan="2" align="center"| 18,026
| colspan="2"| 1,299
| colspan="2" align="center"| 1,299
| colspan="2"| 2,509
| colspan="2" align="center"| 2,509
| colspan="2"| 547
| colspan="2" align="center"| 547
| colspan="2"| 22,381
| colspan="2" align="center"| 22,381
|----
|----
| Females
| Females
| colspan="2"| 13,141
| colspan="2" align="center"| 13,141
| colspan="2"| 984
| colspan="2" align="center"| 984
| colspan="2"| 2,177
| colspan="2" align="center"| 2,177
| colspan="2"| 344
| colspan="2" align="center"| 344
| colspan="2"| 16,646
| colspan="2" align="center"| 16,646
|----
|----
| Persons
| Persons
| colspan="2"| 31,167
| colspan="2" align="center"| 31,167
| colspan="2"| 2,283
| colspan="2" align="center"| 2,283
| colspan="2"| 4,686
| colspan="2" align="center"| 4,686
| colspan="2"| 891
| colspan="2" align="center"| 891
| colspan="2"| 39,027
| colspan="2" align="center"| 39,027
|----
|----
| colspan="12"| Crude rate per 100,000 population
| colspan="12"| Crude rate per 100,000 population
|----
|----
| Males
| Males
| colspan="2"| 72.3
| colspan="2" align="center"| 72.3
| colspan="2"| 89.9
| colspan="2" align="center"| 89.9
| colspan="2"| 101.6
| colspan="2" align="center"| 101.6
| colspan="2"| 64.1
| colspan="2" align="center"| 64.1
| colspan="2"| 75.4
| colspan="2" align="center"| 75.4
|----
|----
| Females
| Females
| colspan="2"| 50.9
| colspan="2" align="center"| 50.9
| colspan="2"| 64.7
| colspan="2" align="center"| 64.7
| colspan="2"| 82.2
| colspan="2" align="center"| 82.2
| colspan="2"| 38.7
| colspan="2" align="center"| 38.7
| colspan="2"| 53.9
| colspan="2" align="center"| 53.9
|----
|----
| Persons
| Persons
| colspan="2"| 61.4
| colspan="2" align="center"| 61.4
| colspan="2"| 77.0
| colspan="2" align="center"| 77.0
| colspan="2"| 91.6
| colspan="2" align="center"| 91.6
| colspan="2"| 51.2
| colspan="2" align="center"| 51.2
| colspan="2"| 64.4
| colspan="2" align="center"| 64.4
|----
|----
| colspan="12"| Age-standardised rate (European) per 100,000 population
| colspan="12"| Age-standardised rate (European) per 100,000 population
|----
|----
| Males
| Males
| colspan="2"| 58.3
| colspan="2" align="center"| 58.3
| colspan="2"| 65.8
| colspan="2" align="center"| 65.8
| colspan="2"| 81.7
| colspan="2" align="center"| 81.7
| colspan="2"| 60.8
| colspan="2" align="center"| 60.8
| colspan="2"| 60.8
| colspan="2" align="center"| 60.8
|----
|----
| 95% CI
| 95% CI
Line 229: Line 229:
|----
|----
| Females
| Females
| colspan="2"| 35.0
| colspan="2" align="center"| 35.0
| colspan="2"| 40.9
| colspan="2" align="center"| 40.9
| colspan="2"| 55.1
| colspan="2" align="center"| 55.1
| colspan="2"| 31.5
| colspan="2" align="center"| 31.5
| colspan="2"| 37.1
| colspan="2" align="center"| 37.1
|----
|----
| 95% CI
| 95% CI
Line 248: Line 248:
|----
|----
| Persons
| Persons
| colspan="2"| 45.2
| colspan="2" align="center"| 45.2
| colspan="2"| 51.9
| colspan="2" align="center"| 51.9
| colspan="2"| 66.2
| colspan="2" align="center"| 66.2
| colspan="2"| 44.3
| colspan="2" align="center"| 44.3
| colspan="2"| 47.4
| colspan="2" align="center"| 47.4
|----
|----
| 95% CI
| 95% CI

Revision as of 08:22, 30 June 2010



Scope

What is the incidence of lung cancer in the general population?

Definition

Rate (age, sex ratio) Context (population size studied, location, date data taken, end-point measured) Definition of end-point Reference
375,000 cases (estimate)
303,000 in men
72,000 in women
Estimated number of resulting deaths = 347,000 (280,000 in men and 67,000 in women).
Estimates of lung-cancer incidence in Europe, 2000
Men Women
Country Crude rate ASR Cumulative risk* No of cases Crude rate ASR Cumulative risk* No of cases
Eastern Europe 87.2 69•7 4•4 126 653 79•2 63•1 3•8 115 091
Northern Europe 73.5 44•3 1•9 33 976 75•7 45•1 1•8 35 007
Southern Europe 95.9 58•8 3•2 67 518 84•4 50•4 2•5 59 426
Western Europe 83.9 53•2 2•9 75 350 79•1 48•9 2•3 71 024
*Cumulative risks are for ages 0–64 years. ASR, age-standardised rate.
Europe, 2000 J.Tyczynski, F.Bray, D.Maxwell Parkin. Lung cancer in Europe in 2000: epidemiology, prevention, and early detection. The Lancet Oncology, Volume 4, Issue 1, Pages 45-55.
Relative risk of lung cancer in European men and women
Men Women
Squamous-cell and small-cell carcinoma Adenocarcinoma Squamous-cell and small-cell carcinoma Adenocarcinoma
Non-smoker 1•0 1•0 1•0 1•0
Ex-smoker 16•2* 3•5* 3•8* 1•1
Current smoker 57•9* 8•0* 18•2* 4•1*
* p<0•05
Table 2. Effects of smoking cessation on lung-cancer risk
Relative risk
Time since stopping Men Women
Current smokers 1•00 1•00
2–9 years 0•66* 0•41*
10–19 years 0•27* 0•19*
20–29 years 0•17* 0•08*
>30 years 0•08* 0•13*
Non-smokers 0•04* 0•11*
* p<0•05
n=7,609 with 10,431 controls, 10 case-control studies of lung cancer in 6 countries from 1988 to 1994: Sweden, Germany, United Kingdom, France, Spain, Italy. Lung cancer Simonato L, Agudo A, Ahrens W, et al. Lung cancer and cigarette smoking in Europe: an update of risk estimates and an assessment of inter-country heterogeneity. Int J Cancer 2001; 91: 876–87.
border="2" cellspacing="0" cellpadding="3" rules="all" style="margin:0em 1em 1em 1em; border:solid 1px #AAAAAA; border-collapse:collapse;background-color:#F9F9F9; font-size:90%; empty-cells:show;" Number of new cases and rates of lung cancer, UK, 2006
England Wales Scotland N.Ireland UK
Cases
Males 18,026 1,299 2,509 547 22,381
Females 13,141 984 2,177 344 16,646
Persons 31,167 2,283 4,686 891 39,027
Crude rate per 100,000 population
Males 72.3 89.9 101.6 64.1 75.4
Females 50.9 64.7 82.2 38.7 53.9
Persons 61.4 77.0 91.6 51.2 64.4
Age-standardised rate (European) per 100,000 population
Males 58.3 65.8 81.7 60.8 60.8
95% CI 57.5 59.2 62.2 69.4 78.5 84.9 55.7 65.9 60.0 61.5
Females 35.0 40.9 55.1 31.5 37.1
95% CI 34.4 35.6 38.3 43.4 52.8 57.4 28.2 34.9 36.5 37.6
Persons 45.2 51.9 66.2 44.3 47.4
95% CI 44.7 45.7 49.8 54.0 64.3 68.1 41.4 47.2 46.9 47.9

| UK, 2006, lunch cancer | Doctor diagnosed | http://info.cancerresearchuk.org/cancerstats/types/lung/incidence/index.htm |---- | INCIDENCE | MORTALITY |---- | MALE | FEMALE | MALE | FEMALE |---- | ASR | Cumulative risk | ASR | Cumulative risk | ASR | Cumulative risk | ASR | Cumulative risk |---- | (World) | (age 0–64) | (World) | (age 0-64) | (World) | (age 0–64) | (World) | (age 0-64) |---- | E. Europe | 257.7 | 14.1 | 175.1 | 10.8 | 197.2 | 10.4 | 101.9 | 5.6 |---- | N. Europe | 283.1 | 11.7 | 252.3 | 14.0 | 161.0 | 5.8 | 118.1 | 5.2 |---- | S. Europe | 299.4 | 14.2 | 208.1 | 12.0 | 170.1 | 7.1 | 92.2 | 4.2 |---- | W. Europe | 326.4 | 15.5 | 244.6 | 14.1 | 173.9 | 7.0 | 106.1 | 4.6 |---- | World | 209.6 | 10.3 | 161.5 | 9.5 | 137.7 | 6.4 | 92.1 | 4.9 |---- | Worldwide, 1993-2001 with population estimates from 2002 to estimate 2002 cancer burden, from GLOBOCAN database, lung cancer | | D. Max Parkin, Freddie Bray, J. Ferlay and Paola Pisani. Global Cancer Statistics, 2002. CA Cancer J Clin. 2005;55;74-108 |---- | Total prevalence by country and age class. Proportions per 100000 persons |---- | Men | Women |---- | 0-44 | 45-64 | 65+ | All ages | 0-44 | 45-64 | 65+ | All ages |---- | Netherlands | 3.3 | 276.5 | 1468.0 | 197.4 | 3.1 | 79.3 | 101.1 | 33.1 |---- | Germany | 5.6 | 246.5 | 907.4 | 168.0 | 2.3 | 51.3 | 100.1 | 33.1 |---- | Austria | 5.7 | 201.5 | 610.0 | 103.1 | 3.9 | 68.9 | 111.1 | 33.9 |---- | Switzerland | 6.4 | 215.0 | 721.6 | 145.8 | 3.4 | 71.6 | 144.0 | 45.9 |---- | Slovenia | 7.5 | 262.1 | 672.0 | 118.9 | 1.5 | 36.1 | 60.5 | 17.8 |---- | Slovakia | 6.3 | 398.6 | 1390.4 | 206.5 | 2.0 | 40.3 | 141.5 | 28.1 |---- | Poland | 5.5 | 216.2 | 424.5 | 100.0 | 2.9 | 57.3 | 103.9 | 32.6 |---- | All Euro countries (n=17) | 3.8 | 201.5 | 791.5 | 144.1 | 2.2 | 59.7 | 166.1 | 44.2 |---- | Austria, Germany, The Netherlands, Poland, Slovakia, Slovenia and Switzerland, 1970-1992, lung cancer | | J. M. Lutz, S. Francisci, E. Mugno, M. Usel, V. Pompe-Kirn, J.-W. Coebergh & M. Bieslka-Lasota. Cancer prevalence in Central Europe: the EUROPREVAL Study. Annals of Oncology, 2003, 14: 313–322. |---- |}

Result

{{#opasnet_base_link:Op_en4536}}


See also

Related files

<mfanonymousfilelist></mfanonymousfilelist>


References

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