Economic evaluation: Difference between revisions

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== Question ==


== Kysymys ==
If a vaccine product is more effective, but also more expensive, when are the additional benefits worth the excess cost?
* The benefits are assessed from the decrease of cases of pnaumococcal deseases following the extensive use of the vaccine. Benefit (effectiveness) is measured in Quality-Adjusted Life Years (QALYs)
* Health care costs are the only costs taken into account. 


Jos rokotevalmiste on vaikuttavuudeltaan parempi mutta tarjotultaan hinnaltaan kalliimpi, milloin sillä saavutettu lisähyöty on lisäkustannuksen arvoinen?
== Answer ==
* Hyötyä arvioidaan rokotteen laajamittaisesta käytöstä seuraavalla invasiivisen pneumokokkitautitapausten vähenemisellä koko väestössä. Hyötyä eli vaikuttavuutta mitataan muutoksella laatupainotetuissa elinvuosissa (Quality-Adjusted Life Years, QALYs).
* Kustannuksista otetaan huomioon vain terveydenhuollon kustannukset. 


== Vastaus ==
To find the most cost-effective product according to the crieria described in the rationale.


Etsitään kustannusvaikuttavin valmiste perusteluissa kuvattujen kriteerien mukaisesti.
== Rationale ==


== Perustelu ==
Products are arranged accordin to effectiveness (V<sub>1</sub> < V<sub>2</sub> < V<sub>3</sub>, etc.). With the product's incremental cost-effectiveness ratio (ICER; unit €/QALY) the product's effectiveness is comaperd to the next more effective product. ICER is calculated by dividing the difference between costs with the difference between health effects:
 
Valmisteet järjestetään vaikuttavuuden mukaan (V<sub>1</sub> < V<sub>2</sub> < V<sub>3</sub>, jne). Valmisteen inkrementaalisessa kustannusvaikuttavuussuhteessa (incremental cost-effectiveness ratio, ICER; yksikkönä €/QALY) valmistetta verrataan vaikuttavuudeltaan seuraavaksi parempaan valmisteeseen. ICER lasketaan jakamalla kustannusten erotus terveysvaikutusten erotuksella:


<math>ICER = \frac{(C_2-S_2) - (C_1-S_1)}{E_2-E_1},</math>
<math>ICER = \frac{(C_2-S_2) - (C_1-S_1)}{E_2-E_1},</math>


  missä C on rokotusohjelman hinta, S on säästö hoitokustannuksissa ja E on QALY-säästö.
  where C is the prize of the vaccinating progranm, S is the savings in health care costs and E is the savings on QALY.


Vaikuttavuudeltaan parempi ja hinnaltaan kalliimpi valmiste (V<sub>2</sub>) valitaan, jos päätöksentekijöiden mielestä sillä saavutettu lisävaikuttavuus on sen aiheuttaman lisäkustannuksen arvoinen eli ICER < hyväksyttävä rajakustannus.
The more effective and more expensive product (V<sub>2</sub>) is chosen, if the decision makers think the additional effectiveness is worth the excess cost, meaning ICER < acceptable marginal cost.


== See also ==
== See also ==


{{pneumococcal vaccine}}
{{pneumococcal vaccine}}

Revision as of 11:40, 21 June 2014

Question

If a vaccine product is more effective, but also more expensive, when are the additional benefits worth the excess cost?

  • The benefits are assessed from the decrease of cases of pnaumococcal deseases following the extensive use of the vaccine. Benefit (effectiveness) is measured in Quality-Adjusted Life Years (QALYs)
  • Health care costs are the only costs taken into account.

Answer

To find the most cost-effective product according to the crieria described in the rationale.

Rationale

Products are arranged accordin to effectiveness (V1 < V2 < V3, etc.). With the product's incremental cost-effectiveness ratio (ICER; unit €/QALY) the product's effectiveness is comaperd to the next more effective product. ICER is calculated by dividing the difference between costs with the difference between health effects:

Failed to parse (SVG (MathML can be enabled via browser plugin): Invalid response ("Math extension cannot connect to Restbase.") from server "https://wikimedia.org/api/rest_v1/":): {\displaystyle ICER = \frac{(C_2-S_2) - (C_1-S_1)}{E_2-E_1},}

where C is the prize of the vaccinating progranm, S is the savings in health care costs and E is the savings on QALY.

The more effective and more expensive product (V2) is chosen, if the decision makers think the additional effectiveness is worth the excess cost, meaning ICER < acceptable marginal cost.

See also

Tendering process for pneumococcal conjugate vaccine
Parts of the assessment

Comparison criteria for vaccine   · Epidemiological modelling   · Economic evaluation

Background information

Sensitivity analysis · Replacement   · Pneumococcal vaccine products   · Finnish vaccination schedule   · Selected recent publications


Help for discussion and wiki editing

Pages in Finnish

Pneumokokkirokotteen hankinta  · Rokotteen vertailuperusteet · Epidemiologinen malli · Taloudellinen arviointi · Pneumokokkirokotteen turvallisuus


Work scheduling · Monitoring the effectiveness of the pneumococcal conjugate vaccine · Glossary of vaccine terminology